The Exemestane Guide: How It Works, Positive Effects, and Warnings
Exemestane was first launched in 1997 and is used for the treatment of breast cancer in postmenopausal women. It’s sold under the brand name Aromasin. It was founded by the pharmaceutical company Pfizer.
Exemestane is used for treating breast cancer in certain women who have gone through menopause, including those with disease progression after tamoxifen therapy.
Defining what Exemestane is
Exemestane is a medication that is used to treat breast cancer in postmenopausal women. It is also used to prevent breast cancer from coming back in women who have already been treated for this condition.
Exemestane belongs to a group of drugs called aromatase inhibitors. This medication works by blocking the production of estrogen, which helps slow or stop the growth of certain types of breast cancers that need estrogen to grow and spread.
It is a selective estrogen receptor modulator which inhibits the action of estrogen in breast tissue. It has been used since 1997 and it is a nonsteroidal, antiestrogen agent.
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Why is Exemestane a great choice?
Exemestane is a type of drug that is usually prescribed to women who have been diagnosed with breast cancer. It is a good choice because it has lower risk of causing venous thromboembolism and it can be taken as a long-term treatment.
This medication has been shown to be effective in treating breast cancer and has fewer side effects than other treatments. It can also be used for extended periods of time without the need for breaks. This drug blocks an enzyme called aromatase which is responsible for making estrogen, thereby reducing the amount of estrogen in your body.
Exemestane is also used as a treatment for advanced prostate cancer in males with hormone sensitive tumors and is often utilized in combination with an aromatase inhibitor (e.g. Aromasin) or as a monotherapy for those who cannot tolerate such drugs (Estroblock).
Read more about Exemestane in bodybuilding
How Exemestane works inside the body?
Exemestane is used to treat breast cancer in postmenopausal women, including those with disease progression after taking tamoxifen. Exemestane belongs to a class of drugs called aromatase inhibitors. This medication works by blocking the production of estrogen, which helps slow or stop the growth of certain types of breast cancers that need estrogen to grow and spread.
It is a selective estrogen receptor modulator which inhibits the action of estrogen in breast tissue. It has been used since 1997 and it is a nonsteroidal, antiestrogen agent. It works in part by reducing the amount of certain hormones made by your ovaries.
Exemestane lowers levels of estrogen in the body. The most important sign of estrogen-positive breast cancer is increased levels of a hormone called estradiol in the blood, which may be measured by an endocrine (hormone) specialist. Exemestane lowers both estrone and estradiol by blocking the enzyme aromatase, which forms estrogen in your body.
The positive effects of using Exemestane
There have been case reports of the following benefits when using Exemestane. It can reduce estrogen in postmenopausal women who are at high risk for developing breast cancer after taking tamoxifen or other medicines.
It has also shown to be beneficial in controlling advanced prostate cancer (for men), where it is often used in combination with other drugs, including an aromatase inhibitor (e.g., Aromasin).
It can reduce the risk of early death in people with prostate cancer; however, there is no evidence it can improve overall survival or extend life by more than a few months. There are also reports that Exemestane has positive effects on bone density and cardiovascular parameters in men with advanced prostate cancer.
Some low-dose combinations of Exemestane and anastrozole are well tolerated by postmenopausal women with hormone receptor-positive, estrogen receptor-negative breast cancer.
Furthermore, it can give you more energy, improve your skin and hair, build stronger bones (by speeding up the rate at which bone is broken down and re-formed), help maintain sexual function for many women.
Lastly, since the side effects of Exemestane are rare and mild, people taking it tend to stick with it. This means it will prevent estrogen levels from rising again in your body.
The potential side effects of abusing Exemestane
Exemestane is safe but may cause mild side effects. These effects usually go away with continued treatment, but if they are too bothersome or do not disappear, consult your doctor for advice on reducing the dose or stopping the medication.
Exemestane use may be linked with increased risk of blood clots, strokes, or heart attacks because it lowers the amount of estrogen in your body. This medication can cause liver problems including hepatitis. It can also cause serious birth defects if used during pregnancy.
Side effects of abusing Exemestane can include:
- Hair loss
- Loss of appetite
- Nausea and vomiting
- Headache or dizziness
- Fever or chills
- Shortness of breath
These side effects should disappear with continued treatment, but if they are too bothersome or do not disappear, consult your doctor for advice on reducing the dose or stopping the medication.
The proper dosage instructions for Exemestane
You should never use Exemestane without first talking to your doctor if you are pregnant or could become pregnant during treatment. Do not use this medicine without first talking to your doctor if you are breast-feeding a baby.
A lab test may give inaccurate or misleading results when you are taking Exemestane. Be sure to tell your doctor and the people running any blood tests.
Exemestane comes in tablet form, taken by mouth once daily at the same time every day for five consecutive days each month. Take it with or without food, as directed by your doctor. Do not take more of it or less of it.
Please be informed that your health care professional will decide for how long you can take Exemestane. If you stop using this medication without consulting with a doctor, it may cause serious side effects to your health.
Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. This medication works best when there is a constant level of Exemestane in your body.
To help you remember, take it at the same time each day (about 12 hours apart).
Do not stop taking this medication without consulting with your physician first.
Your doctor may need to alter your daily dosage of the drug in order to obtain the optimum results.
Usual Adult Dose for Prostate Cancer:
25 mg orally once a day on days 1 through 5 of each month or
1 mg orally once a day on days 1 through 21 of each month, with or without food
Duration of therapy: Until your cancer progresses or cannot be treated by hormone therapy, or your doctor determines that you should discontinue treatment
The recommended dosage in general is 25 mg orally once a day on days 1 through 5 of each month or 1 mg orally once a day on days 1 through 21 of each month, with or without food. There are no data available to recommend the use of more than one dose daily for any reason including the avoidance of “pill burden”.
It may take between 2 weeks and 4 months for this medication to reduce the size of your prostate cancer and for you to notice an effect. Your doctor may tell you to stop taking this drug once the benefits of treatment appear and/or you relapse after stopping therapy.
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Can Exemestane be stacked for better results?
Exemestane can be stacked to achieve a better dosage or effect.
The following cycle is an example of how to stack Exemestane with Arimidex and Nolvadex:
Week 1-12: 25mg/day (exemestane) + 0.5mg/EOD (arimidex)
Week 13: 50mg/day (exemestane) + 0.5mg/EOD (arimidex)
Week 14: Off (so nothing)
Week 15: 50mg/day (exemestane) + 0.5mg/EOD (arimidex)
Week 16: 100mg/day (exemestane) + 0.5mg/EOD (arimidex)
(Note that the dosage of exemestane is increased, while arimidex remains at 0.5mg EOD.)
Is it okay to stack with Dianabol?
No, don’t stack Exemestane with Dianabol unless you want to fry your liver.
Exemestane cycle for Cutting
Take 25mg/day for 4-8 weeks.
You can also stack this drug with Anavar, Winstrol, Dianabol.
For example, the following cycle is suitable for men who are looking to maintain their gains after bulking up with Dianabol:
Week 1-12: 50mg/day (exemestane)
Week 13: 50mg/day (exemestane) + 20mg/day (dianabol/mastabolin/Stanozolol) + 2.5mg/EOD (arimidex)
This cycle is also effective if you are looking to burn fat as well as maintain and protect lean mass:
Exemestane + Trenbolone (75mg/day) + Testosterone propionate (150mg/week) for 9 weeks.
Exemestane Cycle for Bulking
100 mg/ day of exemestane will be the best choice if you are looking for a safe, side-effect free bulking steroid cycle.
You can stack this drug with Dianabol or Anadrol for up to 6-8 weeks until you get the desired results.
However, you will probably experience noticeable estrogenic side effects which would be bothersome if combined with other anabolic steroids.
If this is the case, you may stack it with Proviron or Cytomel (T3) which are anti-estrogenic.
The following bulking cycle is suitable for men who are looking to gain hard lean muscle mass:
Week 1-12: 100mg/day (exemestane) + 200mg/week (Dianabol/Anadrol) + 100mcg/day (T3)
Is Exemestane a legal supplement?
Yes, Exemestane is a legal supplement which can be purchased in many countries.
However, the quality and composition of the product may vary in different countries because it is not regulated by relevant authorities such as FDA (USA) and MHRA (UK).
For this reason, make sure you only purchase the best quality supplements from your local trusted supplier.
Warnings and Precautions for Exemestane
Before you start taking Exemestane, let your doctor know if any of the following conditions apply to you:
kidney or liver disease;
very high cholesterol or triglyceride levels;
a personal history or hereditary predisposition toward diabetes;
a history of depression;
risk factors for heart disease such as smoking, obesity, family history of heart disease, or abnormal menstrual cycles;
risk factors for osteoporosis such as smoking, not enough exercise, poor diet, family history of osteoporosis or early menopause.
Product reviews for Exemestane
- Gerald Anderson (June 7, 2021): “I’ve been taking Exemestane for the past year and I’m happy with it. It’s not perfect, but it does what it needs to do. I’ve had some side effects like weight gain and acne, but that’s to be expected. The benefits outweigh the cons for me.”
- Tony Larusca (July 26, 2021): “I have been using Exemestane for a while now and it has been a lifesaver. I was looking for something to help me keep my estrogen levels in check and this is the only thing that has helped. I’ve seen so many improvements in my energy levels, mood, and overall health since I started taking it. It’s also really affordable!”
- Annie Perez (August 3, 2021): “This is a great drug. I’ve been taking it for over a year and it’s been the most effective treatment for me so far. My doctor recommends this drug to all of his patients who have breast cancer.”
- Isabella Tyler (August 18, 2021): “I’ve been taking Exemestane for a few months now and it has helped me tremendously with my PCOS symptoms. I don’t need to take metformin anymore and I’m not as moody as I used to be. It’s also really easy to take, no big deal.”
- Chloe Wood (September 12, 2021): “I have been using Exemestane for a while now and I’m so happy with the results. I lost weight, my hair started growing back, and my skin became healthier. I would recommend this drug to anyone looking to lose weight and get healthier.”
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Frequently Asked Questions about Exemestane
Q: What does it do?
A: Exemestane is a steroid which reduces estrogen levels in the body. It helps to protect the muscles from losing protein, so it’s good for cutting.
It also increases appetite and improves energy levels.
Q: Is Exemestane legal?
A: Yes, Exemestane is a legal steroid which can be purchased by any adult.
Q: How does it work?
A: Exemestane helps to reduce estrogen levels in the body and increase testosterone levels, which will lead to increased muscle mass and strength.
It also increases energy levels so you’ll get more out of your workouts.
Q: Half-life of Exemestane?
A: The half-life of exemestane is 24-36 hours.
Q: How do you take exemestane?
A: Exemestane should be taken orally once per day for 6-8 weeks.
Q: How long does it stay in your body?
A: It stays in the body for about 24-36 hours.
Summary and Conclusion
Exemestane is an effective steroid which helps to reduce estrogen levels in the body. It’s also great for cutting because it increases appetite and improves energy levels. It is the best steroid for men looking to gain hard lean muscle mass. And the best for women looking to reduce their estrogen levels.
Exemestane is a legal steroid which can be purchased in most countries. Make sure you purchase the best quality supplements from your local trusted supplier.
Make sure you read all the instructions carefully and follow the right dosage to get the best results without any side effects.
It’s also important to consult with your doctor before using exemestane, especially if you have preexisting health conditions.
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